Order details will show information about the order, and a reminder of that there are products in the order without a response.
Order lines with changes will be marked with an icon for +- in the column for "Quantity" and the new quantity requested by the buyer will be shown on the left to the icon.
"Conf. qty" will still show the quantity confirmed in the latest order response if an order response has been sent.
Hover the mouse over the icon to see the original quantity.
Note that statuses for order lines can be changed to “New” even though an order response has been sent with other statuses.
It all depends on the information sent in the order change from the buyer.
More information:
How to see in the list of orders that an order change has been received?
What to take notice of when created an order response from an order with order changes?